Across TCGA pan-cancer cohorts, SNORD83A RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated SNORD83A data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher SNORD83A RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNORD83A expression acts as an unfavorable survival marker, although some lineages such as BLCA and UCS show a favorable association.

UVM, KIRC, and KIRP are the cancer types where SNORD83A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	III,IV	0.315	0.715	.001	85	view →
KIRC	DFS	Median	All	0.528	0.695	.001	82	view →
KIRP	DFS	Median	III,IV	0.128	0.651	<.001	68	view →
BLCA	DFS	Tertile	III,IV	0.452	0.215	.006	61	view →
UCS	OS	Median	III,IV	0.543	0.200	.006	50	view →
LUAD	OS	Quartile	II,III,IV	0.865	0.503	.004	37	view →
ACC	DFS	Quartile	All	0.391	0.729	.011	35	view →
COAD	DFS	Median	III,IV	0.440	0.767	<.001	33	view →
STAD	OS	Median	All	0.638	0.411	.005	20	view →
CESC	DFS	Median	III,IV	0.237	0.661	.010	16	view →
PRAD	DFS	Median	All	0.841	0.924	.002	16	view →
SKCM	DFS	Tertile	II,III,IV	0.147	0.272	.012	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

Exploration

Same gene, other analysis: SNORD83A tumor-vs-normal RNA expression · all SNORD83A data types