Across TCGA pan-cancer cohorts, SNORD8 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated SNORD8 data layer.
The strongest signal is observed in stomach adenocarcinoma (STAD), where higher SNORD8 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNORD8 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LUSC show a favorable association.
STAD, KIRP, and DLBC are the cancer types where SNORD8 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.