Across TCGA pan-cancer cohorts, SNORD71 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of SNORD71’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where SNORD71 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNORD71 is over-expressed in tumor, although a few such as THCA and KIRP show the opposite, repressed pattern.

STAD, COAD, and THCA are the cancer types where SNORD71 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORD71 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	II,III,IV	+0.762	<.001	6	view →
COAD	All	All	+0.491	.009	2	view →
THCA	Female	All	−0.187	.014	2	view →
HNSC	All	All	+0.183	.015	2	view →
KIRP	All	III,IV	−0.331	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: SNORD71 RNA expression & survival · all SNORD71 data types