SNORD42B

Across TCGA pan-cancer cohorts, SNORD42B RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of SNORD42B’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where SNORD42B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNORD42B is over-expressed in tumor, although a few such as LUAD and LIHC show the opposite, repressed pattern.

BLCA, COAD, and UCEC are the cancer types where SNORD42B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORD42B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	All	+0.601	.022	5	view →
COAD	Female	All	+0.788	.003	3	view →
UCEC	All	III,IV	+0.976	.049	2	view →
LUAD	All	III,IV	−0.464	.034	2	view →
BRCA	All	All	+0.238	.015	2	view →
PRAD	All	All	+0.221	.014	2	view →
READ	All	All	+1.007	.036	1	view →
LIHC	Female	All	−0.118	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

SNORD42B–BLCA

Open the BLCA breakdown →