small nucleolar RNA, C/D box 15BGenealiases: RNU15B · U15B
Q-omics provides the consensus-scored SNORD15B profile across patient tissues and cancer cell-line models. SNORD15B expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, SNORD15B is differentially expressed in 11, with the highest sampling consensus in COAD. Additionally, SNORD15B RNA expression shows 11,625 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, COAD, and THYM as cancer lineages where SNORD15B shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SNORD15B — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SNORD15B survival associations across molecular data types. SNORD15B RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SNORD15B RNA expression–survival associations across cancer types. High SNORD15B expression shows unfavorable associations in KIRC, KIRP, ACC, OV, PRAD and MESO. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for SNORD15B RNA expression.
This table summarizes SNORD15B tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for SNORD15B. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SNORD15B shows higher tumor expression in COAD, READ, LUSC, BLCA, ESCA and HNSC. The COAD box plot shows higher SNORD15B RNA expression in tumor versus normal tissue (log2 FC = +1.365, t-test p < 0.001).
This table shows molecular features associated with SNORD15B in patient tissues and cancer cell lines. In patient samples, SNORD15B shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
