Q-omics provides the consensus-scored SNORD14E profile across patient tissues and cancer cell-line models. SNORD14E expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, SNORD14E is differentially expressed in 13, with the highest sampling consensus in HNSC. Additionally, SNORD14E RNA expression shows 13,877 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight ACC, HNSC, and UVM as cancer lineages where SNORD14E shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SNORD14E — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SNORD14E survival associations across molecular data types. SNORD14E RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SNORD14E RNA expression–survival associations across cancer types. High SNORD14E expression shows unfavorable associations in ACC, COAD, HNSC, MESO, KIRP and KIRC. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for SNORD14E RNA expression.
This table summarizes SNORD14E tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for SNORD14E. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SNORD14E shows higher tumor expression in HNSC, BLCA, STAD, COAD, LUAD and UCEC. The HNSC box plot shows higher SNORD14E RNA expression in tumor versus normal tissue (log2 FC = +1.539, t-test p < 0.001).
This table shows molecular features associated with SNORD14E in patient tissues and cancer cell lines. In patient samples, SNORD14E shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
