SNORD121B

Across TCGA patient cohorts, SNORD121B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,803 significant associations in total. OV shows the largest number of these associations.

The most reproducible SNORD121B-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Golgi vesicle transport, and Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway. Each is linked with SNORD121B in more than 26 cancer types. Because this analysis shows association rather than direction, both SNORD121B-to-partner and partner-to-SNORD121B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by SNORD121B-low versus SNORD121B-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD121B→partner) and Y-score (partner→SNORD121B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Positive regulation of double-strand break repair →	+0.059	+0.501	.001	<.001	2	27
THYM	Golgi vesicle transport →	+0.054	+0.574	<.001	<.001	3	26
DLBC	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.076	+0.486	<.001	.002	3	25
ESCA	Protein localization to microtubule organizing center →	+0.052	+0.512	<.001	<.001	3	25
DLBC	Regulation of double-strand break repair →	+0.051	+0.386	.003	.004	3	25
THYM	Regulation of nucleotide-excision repair →	+0.053	+0.402	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,803 associations by consensus.

Positive regulation of double-strand break repair by SNORD121B expression — DLBC

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