SNORD121A

Across TCGA pan-cancer cohorts, SNORD121A RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated SNORD121A data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher SNORD121A RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SNORD121A expression acts as an unfavorable survival marker, although some lineages such as OV and LUAD show a favorable association.

OV, LIHC, and SKCM are the cancer types where SNORD121A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Tertile	III,IV	0.627	0.501	.005	52	view →
LIHC	DFS	Tertile	All	0.376	0.569	<.001	39	view →
SKCM	DFS	Tertile	IV	0.055	0.515	.005	37	view →
MESO	OS	Tertile	IV	0.077	0.638	<.001	36	view →
THCA	OS	Tertile	All	0.635	0.959	.013	29	view →
UVM	OS	Tertile	All	0.332	0.741	.015	27	view →
LUAD	DFS	Quartile	III,IV	0.804	0.548	.002	22	view →
READ	OS	Median	IV	1.000	0.676	.003	21	view →
KIRC	DFS	Quartile	IV	0.282	0.546	<.001	18	view →
KIRP	DFS	Tertile	All	0.323	0.653	.004	18	view →
TGCT	DFS	Median	II,III,IV	0.740	1.000	.022	14	view →
SARC	OS	Tertile	All	0.554	0.812	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

SNORD121A–OV (DFS)

Open the OV breakdown →