SNORD11B

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SNORD11B RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated SNORD11B data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher SNORD11B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD11B expression acts as an unfavorable survival marker, although some lineages such as SKCM and ESCA show a favorable association.

DLBC, MESO, and LIHC are the cancer types where SNORD11B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
DLBCOSTertileAll0.5391.000.00264view →
MESOOSQuartileII,III,IV0.3760.618.00360view →
LIHCOSTertileAll0.5380.810.00157view →
UCECDFSTertileAll0.7420.859.00148view →
PRADOSTertileAll0.9670.995.00930view →
THCADFSTertileIV0.6010.961.01118view →
SKCMDFSTertileIII,IV0.3960.174.01215view →
BLCADFSQuartileII,III,IV0.5490.633.02515view →
PCPGDFSTertileAll0.8480.939.0229view →
UVMOSTertileIII,IV0.3110.906.0226view →
ESCADFSTertileAll1.0000.503.0275view →
SARCDFSTertileAll0.4870.276.0383view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

SNORD11B–DLBC (OS)

Kaplan–Meier survival curve for SNORD11B RNA-high vs -low samples in DLBC.

Open the DLBC breakdown →

Exploration