SNORD116-25

Across TCGA pan-cancer cohorts, SNORD116-25 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SNORD116-25 data layer compared with 7 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher SNORD116-25 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD116-25 expression acts as an unfavorable survival marker.

LUSC and SKCM are the cancer types where SNORD116-25 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	III,IV	0.112	0.664	.003	20	view →
SKCM	OS	Median	All	0.233	0.787	.003	15	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SNORD116-25–LUSC (OS)

Open the LUSC breakdown →