SNORD116-25

Across TCGA patient cohorts, SNORD116-25 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,437 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SNORD116-25-associated GO terms across cancer lineages are Negative regulation of telomere maintenance, Obsolete selective autophagy, and Regulation of telomere maintenance via telomere lengthening. Each is linked with SNORD116-25 in more than 14 cancer types. Because this analysis shows association rather than direction, both SNORD116-25-to-partner and partner-to-SNORD116-25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of telomere maintenance grouped by SNORD116-25-low versus SNORD116-25-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-25→partner) and Y-score (partner→SNORD116-25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of telomere maintenance →	+0.098	+0.193	<.001	<.001	3	15
STAD	Obsolete selective autophagy →	+0.104	+0.195	<.001	<.001	3	14
STAD	Regulation of telomere maintenance via telomere lengthening →	+0.109	+0.189	<.001	<.001	3	14
STAD	Cellular response to L-leucine →	+0.086	+0.201	<.001	<.001	3	13
ESCA	TOR signaling →	+0.103	+0.307	<.001	.004	3	13
STAD	Autophagy of mitochondrion →	+0.104	+0.187	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,437 associations by consensus.

Negative regulation of telomere maintenance by SNORD116-25 expression — STAD

Explore this box plot interactively →