SNORD116-25

Across TCGA patient cohorts, SNORD116-25 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORD116-25-associated genes across cancer lineages are LINC02563, BPTFP1, and MIR4710. Each is linked with SNORD116-25 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD116-25-to-partner and partner-to-SNORD116-25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02563 grouped by SNORD116-25-low versus SNORD116-25-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-25→partner) and Y-score (partner→SNORD116-25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02563 →	+0.392	+5.420	<.001	.005	3	1
UCEC	BPTFP1 →	+0.154	+5.621	<.001	.004	3	1
UCEC	MIR4710 →	+0.869	+5.031	<.001	.009	3	1
UCEC	MLECP1 →	+0.154	+6.226	<.001	.001	3	1
UCEC	OR6C70 →	+0.075	+5.551	.008	.004	3	1
UCEC	SNORD114-18 →	+0.865	+5.299	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

LINC02563 by SNORD116-25 expression — UCEC

Explore this box plot interactively →