Across TCGA patient cohorts, SNORD116-2 mutation is significantly associated with the RNA expression of many other genes, with 70 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD116-2-associated genes across cancer lineages are SOD1P2, CHCHD2P3, and LINC02632. Each is linked with SNORD116-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD116-2-to-partner and partner-to-SNORD116-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-2→partner) and Y-score (partner→SNORD116-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SOD1P2 →	+0.082	+4.970	<.001	.005	3	2
UCEC	CHCHD2P3 →	+0.242	+4.188	.005	.009	3	1
SKCM	LINC02632 →	+0.009	+5.080	.004	.004	3	1
SKCM	ADI1P1 →	+0.068	+4.867	<.001	.005	3	1
SKCM	FAM138A →	+0.031	+6.219	<.001	<.001	3	1
SKCM	RNU7-26P →	+0.829	+5.075	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 70 associations by consensus.

Exploration

SNORD116-2 survival (RNA) · tumor vs normal (RNA) · all SNORD116-2 data types