Across TCGA patient cohorts, SNORD116-12 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible SNORD116-12-associated genes across cancer lineages are RNU6-129P, RPL17P19, and RN7SL868P. Each is linked with SNORD116-12 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD116-12-to-partner and partner-to-SNORD116-12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-12→partner) and Y-score (partner→SNORD116-12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-129P →	+0.587	+5.151	<.001	.007	3	1
LUSC	RPL17P19 →	+0.255	+5.548	<.001	.004	3	1
LUSC	RN7SL868P →	+0.254	+5.038	<.001	.009	3	1
LUSC	RNU6-693P →	+0.708	+6.081	<.001	.002	3	1
LUSC	BUD31P1 →	+0.299	+5.792	<.001	.003	3	1
LUSC	MIR548Y →	+0.367	+5.273	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

SNORD116-12 survival (RNA) · tumor vs normal (RNA) · all SNORD116-12 data types