SNORD116-11

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD116-11 mutation is significantly associated with the RNA expression of many other genes, with 137 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible SNORD116-11-associated genes across cancer lineages are MIR1298, RNU6-452P, and MIR3927. Each is linked with SNORD116-11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD116-11-to-partner and partner-to-SNORD116-11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-11→partner) and Y-score (partner→SNORD116-11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCMIR1298 →+0.791+8.336<.001<.00132
SKCMRNU6-452P →+0.868+7.816<.001.00832
LUSCMIR3927 →+1.036+5.151<.001.00732
UCECIGHD5-5 →+1.131+8.066<.001.00731
SKCMRBMY1HP →+0.039+7.816<.001.00831
LUSCLINC02871 →+0.691+4.984<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 137 associations by consensus.

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