Across TCGA pan-cancer cohorts, SNORD116-10 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SNORD116-10 data layer compared with 12 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher SNORD116-10 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD116-10 expression acts as an unfavorable survival marker.

BLCA, LUAD, and SKCM are the cancer types where SNORD116-10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.059	0.720	<.001	24	view →
LUAD	OS	Median	All	0.150	0.788	<.001	18	view →
SKCM	OS	Median	All	0.179	0.781	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SNORD116-10 tumor-vs-normal RNA expression · all SNORD116-10 data types