Across TCGA patient cohorts, SNORD115-8 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-8-associated genes across cancer lineages are MIR8061, GEMIN2P1, and MMEL1-AS1. Each is linked with SNORD115-8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-8-to-partner and partner-to-SNORD115-8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-8→partner) and Y-score (partner→SNORD115-8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR8061 →	+0.664	+7.219	<.001	<.001	3	1
SKCM	GEMIN2P1 →	+0.058	+5.292	<.001	.006	3	1
SKCM	MMEL1-AS1 →	+0.292	+5.594	<.001	.004	3	1
SKCM	LRRC7-AS1 →	+0.187	+6.199	<.001	.001	3	1
SKCM	OR7E117P →	+0.071	+5.771	<.001	.003	3	1
SKCM	RN7SL675P →	+0.156	+6.080	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

SNORD115-8 survival (RNA) · tumor vs normal (RNA) · all SNORD115-8 data types