Across TCGA patient cohorts, SNORD115-5 mutation is significantly associated with the RNA expression of many other genes, with 79 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-5-associated genes across cancer lineages are TSPY12P, NME1P1, and RPS3AP32. Each is linked with SNORD115-5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-5-to-partner and partner-to-SNORD115-5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-5→partner) and Y-score (partner→SNORD115-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TSPY12P →	+0.045	+4.897	<.001	.002	3	1
SKCM	NME1P1 →	+0.089	+5.163	<.001	.002	3	1
SKCM	RPS3AP32 →	+0.038	+3.402	<.001	.007	3	1
SKCM	RPS23P5 →	+0.096	+3.744	<.001	.003	3	1
SKCM	RN7SL228P →	+0.070	+4.671	<.001	.004	3	1
SKCM	PALLD-AS1 →	+0.144	+3.564	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 79 associations by consensus.

Exploration

SNORD115-5 survival (RNA) · tumor vs normal (RNA) · all SNORD115-5 data types