Across TCGA pan-cancer cohorts, SNORD115-47 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SNORD115-47 data layer compared with 8 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher SNORD115-47 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD115-47 expression acts as an unfavorable survival marker.

CESC, UCEC, and LUSC are the cancer types where SNORD115-47 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	All	0.192	0.798	<.001	30	view →
UCEC	OS	Median	II,III,IV	0.231	0.768	.010	24	view →
LUSC	DFS	Median	II,III,IV	0.135	0.663	.015	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SNORD115-47 tumor-vs-normal RNA expression · all SNORD115-47 data types