Across TCGA pan-cancer cohorts, SNORD115-44 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated SNORD115-44 data layer compared with 1 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SNORD115-44 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD115-44 expression acts as an unfavorable survival marker.

KIRC, OV, and KICH are the cancer types where SNORD115-44 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	II,III,IV	0.127	0.806	<.001	108	view →
OV	DFS	Tertile	All	0.156	0.543	<.001	72	view →
KICH	DFS	Tertile	All	0.043	0.971	<.001	72	view →
ESCA	DFS	Tertile	II,III,IV	0.195	0.528	.006	36	view →
STAD	OS	Tertile	All	0.142	0.730	<.001	18	view →
BRCA	DFS	Tertile	II,III,IV	0.661	0.889	.018	12	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: SNORD115-44 tumor-vs-normal RNA expression · all SNORD115-44 data types