Across TCGA pan-cancer cohorts, SNORD115-42 Mutation is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated SNORD115-42 data layer compared with 2 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher SNORD115-42 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD115-42 expression acts as an unfavorable survival marker.

BLCA and LAML are the cancer types where SNORD115-42 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.120	0.720	<.001	48	view →
LAML	DFS	Median	All	0.028	0.572	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SNORD115-42 tumor-vs-normal RNA expression · all SNORD115-42 data types