Across TCGA patient cohorts, SNORD115-31 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-31-associated genes across cancer lineages are RN7SL386P, OR10K2, and DRD5P1. Each is linked with SNORD115-31 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-31-to-partner and partner-to-SNORD115-31 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-31→partner) and Y-score (partner→SNORD115-31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL386P →	+0.224	+5.513	<.001	.004	3	2
SKCM	OR10K2 →	+0.078	+6.328	<.001	.001	3	1
SKCM	DRD5P1 →	+0.047	+5.771	<.001	.003	3	1
SKCM	POTEA →	+0.040	+5.292	<.001	.006	3	1
SKCM	RN7SKP192 →	+0.205	+5.159	<.001	.007	3	1
SKCM	CCDC34P1 →	+0.132	+6.199	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

SNORD115-31 survival (RNA) · tumor vs normal (RNA) · all SNORD115-31 data types