Across TCGA patient cohorts, SNORD115-28 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SNORD115-28-associated genes across cancer lineages are TRIM49D1, DPP10-AS2, and RNU6-1014P. Each is linked with SNORD115-28 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-28-to-partner and partner-to-SNORD115-28 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-28→partner) and Y-score (partner→SNORD115-28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TRIM49D1 →	+0.014	+7.930	<.001	.008	3	1
LUAD	DPP10-AS2 →	+0.054	+7.930	<.001	.008	3	1
LUAD	RNU6-1014P →	+0.280	+7.930	<.001	.008	3	1
LUAD	MIR3612 →	+0.320	+7.930	<.001	.008	3	1
LUAD	MIR4432 →	+0.453	+7.930	<.001	.008	3	1
LUAD	MIR4293 →	+0.352	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

SNORD115-28 survival (RNA) · tumor vs normal (RNA) · all SNORD115-28 data types