SNORD115-24

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD115-24 mutation is significantly associated with the RNA expression of many other genes, with 88 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-24-associated genes across cancer lineages are RNU6ATAC17P, FOXN3P1, and RCC2P3. Each is linked with SNORD115-24 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-24-to-partner and partner-to-SNORD115-24 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-24→partner) and Y-score (partner→SNORD115-24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6ATAC17P →+0.710+4.771<.001.00132
UCECFOXN3P1 →+0.111+4.130.002.00431
SKCMRCC2P3 →+0.069+4.011<.001.00631
SKCMLINC01923 →+0.016+3.913.008.00631
SKCMOR9A1P →+0.095+3.953<.001.00531
SKCMRN7SL754P →+0.208+4.243<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

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