Across TCGA patient cohorts, SNORD115-20 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORD115-20-associated genes across cancer lineages are NUDT4P2, ANAPC1P5, and IGKV2OR2-10. Each is linked with SNORD115-20 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-20-to-partner and partner-to-SNORD115-20 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-20→partner) and Y-score (partner→SNORD115-20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NUDT4P2 →	+0.189	+5.484	<.001	.005	3	1
UCEC	ANAPC1P5 →	+0.263	+5.242	<.001	.007	3	1
UCEC	IGKV2OR2-10 →	+0.189	+5.937	.002	.002	3	1
UCEC	MIR6133 →	+0.618	+4.982	.006	.009	3	1
UCEC	MIR8058 →	+0.736	+5.081	.002	.008	3	1
UCEC	MIR5003 →	+0.700	+5.133	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

SNORD115-20 survival (RNA) · tumor vs normal (RNA) · all SNORD115-20 data types