Across TCGA patient cohorts, SNORD115-10 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-10-associated genes across cancer lineages are RPL31P9, CYMP-AS1, and RNU7-113P. Each is linked with SNORD115-10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-10-to-partner and partner-to-SNORD115-10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-10→partner) and Y-score (partner→SNORD115-10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RPL31P9 →	+0.268	+7.640	<.001	.009	3	1
SKCM	CYMP-AS1 →	+0.032	+5.098	<.001	<.001	3	1
SKCM	RNU7-113P →	+0.909	+3.838	<.001	.009	3	1
SKCM	RN7SL688P →	+0.195	+4.177	.002	.004	3	1
SKCM	RPL21P13 →	+0.200	+4.177	<.001	.004	3	1
SKCM	RN7SL680P →	+0.203	+5.634	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

SNORD115-10 survival (RNA) · tumor vs normal (RNA) · all SNORD115-10 data types