Across TCGA patient cohorts, SNORD114-23 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD114-23-associated genes across cancer lineages are CASKP1, MTCYBP5, and SDAD1P4. Each is linked with SNORD114-23 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD114-23-to-partner and partner-to-SNORD114-23 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD114-23→partner) and Y-score (partner→SNORD114-23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CASKP1 →	+0.166	+5.224	<.001	.007	3	1
SKCM	MTCYBP5 →	+0.057	+5.771	<.001	.003	3	1
SKCM	SDAD1P4 →	+0.040	+5.159	<.001	.007	3	1
SKCM	TUBB8P3 →	+0.074	+5.097	<.001	.008	3	1
SKCM	MIR6737 →	+0.849	+5.867	<.001	.003	3	1
SKCM	KDM5DP1 →	+0.187	+5.224	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

SNORD114-23 survival (RNA) · tumor vs normal (RNA) · all SNORD114-23 data types