Across TCGA pan-cancer cohorts, SNORD113-2 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated SNORD113-2 data layer.
The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SNORD113-2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD113-2 expression acts as an unfavorable survival marker, although some lineages such as UCS and LAML show a favorable association.
LUAD, STAD, and PAAD are the cancer types where SNORD113-2 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.