SNORD112

Across TCGA pan-cancer cohorts, SNORD112 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated SNORD112 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher SNORD112 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNORD112 expression acts as an unfavorable survival marker, although some lineages such as BLCA and PCPG show a favorable association.

LIHC, KICH, and LUSC are the cancer types where SNORD112 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Tertile	All	0.220	0.549	.002	36	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	27	view →
LUSC	DFS	Tertile	III,IV	0.124	0.632	.036	18	view →
MESO	DFS	Tertile	III,IV	0.108	0.428	.001	18	view →
TGCT	DFS	Tertile	III,IV	0.505	1.000	.016	18	view →
BLCA	OS	Tertile	IV	0.508	0.284	.003	15	view →
KIRC	OS	Tertile	All	0.398	0.633	.044	12	view →
PCPG	DFS	Tertile	All	1.000	0.703	.014	11	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	9	view →
LUAD	OS	Tertile	III,IV	0.228	0.677	.015	9	view →
LGG	DFS	Tertile	All	0.200	0.432	.031	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

SNORD112–LIHC (DFS)

Open the LIHC breakdown →