SNORD11

Across TCGA pan-cancer cohorts, SNORD11 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated SNORD11 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SNORD11 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNORD11 expression acts as an unfavorable survival marker, although some lineages such as SKCM and READ show a favorable association.

UCEC, KIRC, and UVM are the cancer types where SNORD11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	All	0.768	0.874	<.001	82	view →
KIRC	DFS	Quartile	II,III,IV	0.385	0.615	.001	42	view →
UVM	OS	Median	All	0.405	0.841	.003	39	view →
CESC	DFS	Tertile	All	0.754	0.898	.001	26	view →
THYM	DFS	Quartile	II,III,IV	0.394	0.889	.001	23	view →
ACC	DFS	Tertile	IV	0.048	0.380	.001	23	view →
SKCM	OS	Median	III,IV	0.513	0.242	.010	20	view →
MESO	OS	Quartile	IV	0.247	0.735	.016	18	view →
READ	OS	Tertile	II,III,IV	0.897	0.315	.003	14	view →
COAD	OS	Tertile	IV	0.741	0.350	.034	12	view →
THCA	DFS	Quartile	III,IV	0.825	0.927	.008	11	view →
BLCA	DFS	Median	II,III,IV	0.284	0.395	.031	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

SNORD11–UCEC (DFS)

Open the UCEC breakdown →