SNORD105B

Across TCGA pan-cancer cohorts, SNORD105B RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SNORD105B’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where SNORD105B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNORD105B is over-expressed in tumor.

STAD, COAD, and LUAD are the cancer types where SNORD105B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORD105B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	II,III,IV	+0.489	<.001	6	view →
COAD	All	All	+0.306	.018	3	view →
LUAD	All	All	+0.263	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

SNORD105B–STAD

Open the STAD breakdown →