Across TCGA pan-cancer cohorts, SNORA80A RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of SNORA80A’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SNORA80A RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNORA80A is over-expressed in tumor, although a few such as ESCA and BLCA show the opposite, repressed pattern.

HNSC, LUAD, and ESCA are the cancer types where SNORA80A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORA80A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.221	<.001	5	view →
LUAD	All	All	+0.484	.021	2	view →
ESCA	All	All	−0.311	.036	2	view →
BRCA	Female	All	+0.215	.039	2	view →
LUSC	All	All	+0.197	.001	2	view →
BLCA	Female	IV	−0.523	.006	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: SNORA80A RNA expression & survival · all SNORA80A data types