SNORA74D

Across TCGA pan-cancer cohorts, SNORA74D RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated SNORA74D data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher SNORA74D RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNORA74D expression acts as an unfavorable survival marker, although some lineages such as ESCA and BLCA show a favorable association.

KICH, UVM, and LIHC are the cancer types where SNORA74D RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	II,III,IV	0.505	0.913	<.001	98	view →
UVM	DFS	Median	All	0.342	0.723	.002	66	view →
LIHC	OS	Tertile	III,IV	0.245	0.569	<.001	63	view →
COAD	DFS	Quartile	II,III,IV	0.388	0.683	.004	27	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
LUAD	OS	Quartile	III,IV	0.502	0.707	.014	18	view →
KIRP	DFS	Tertile	All	0.719	0.892	.007	15	view →
DLBC	DFS	Median	IV	0.128	1.000	.017	14	view →
ESCA	DFS	Quartile	All	0.861	0.213	.028	12	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	10	view →
THCA	OS	Tertile	IV	0.720	1.000	.004	9	view →
BLCA	OS	Tertile	All	0.576	0.378	.027	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

SNORA74D–KICH (OS)

Open the KICH breakdown →