Across TCGA pan-cancer cohorts, SNORA74C-2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SNORA74C-2’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where SNORA74C-2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNORA74C-2 is over-expressed in tumor.

STAD and THCA are the cancer types where SNORA74C-2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORA74C-2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	II,III,IV	+0.313	.006	2	view →
THCA	Female	All	+0.072	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SNORA74C-2 RNA expression & survival · all SNORA74C-2 data types