SNORA74C-1

Across TCGA pan-cancer cohorts, SNORA74C-1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated SNORA74C-1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher SNORA74C-1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNORA74C-1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and STAD show a favorable association.

THCA, MESO, and COAD are the cancer types where SNORA74C-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	II,III,IV	0.458	0.784	<.001	87	view →
MESO	OS	Tertile	IV	0.063	0.683	<.001	63	view →
COAD	DFS	Tertile	All	0.441	0.725	<.001	63	view →
KIRC	DFS	Tertile	III,IV	0.644	0.767	.025	33	view →
LUSC	DFS	Tertile	II,III,IV	0.216	0.427	.011	33	view →
HNSC	OS	Tertile	All	0.240	0.435	.006	27	view →
READ	OS	Tertile	All	0.516	0.918	.003	27	view →
UVM	DFS	Tertile	All	0.210	0.761	.011	18	view →
UCEC	DFS	Tertile	IV	0.213	0.585	.042	18	view →
SKCM	OS	Tertile	III,IV	0.164	0.405	.023	15	view →
ESCA	OS	Tertile	III,IV	0.519	0.302	.043	4	view →
STAD	DFS	Median	III,IV	0.707	0.489	.021	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

SNORA74C-1–THCA (DFS)

Open the THCA breakdown →