Across TCGA pan-cancer cohorts, SNORA70B RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SNORA70B’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SNORA70B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNORA70B is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

COAD, THCA, and BRCA are the cancer types where SNORA70B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORA70B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.382	<.001	8	view →
THCA	Male	III,IV	−0.442	.015	2	view →
BRCA	Female	All	+0.164	.027	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SNORA70B RNA expression & survival · all SNORA70B data types