SNORA59A

Across TCGA pan-cancer cohorts, SNORA59A RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated SNORA59A data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher SNORA59A RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNORA59A expression acts as an unfavorable survival marker, although some lineages such as BLCA and HNSC show a favorable association.

KICH, STAD, and KIRC are the cancer types where SNORA59A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Median	III,IV	0.468	1.000	.001	96	view →
STAD	DFS	Median	III,IV	0.232	0.487	<.001	75	view →
KIRC	DFS	Quartile	IV	0.413	0.751	.001	52	view →
BLCA	DFS	Quartile	All	0.668	0.500	.003	45	view →
HNSC	OS	Quartile	II,III,IV	0.817	0.687	.009	37	view →
LIHC	OS	Quartile	All	0.344	0.669	<.001	32	view →
UCS	DFS	Tertile	IV	0.932	0.296	.024	30	view →
UCEC	DFS	Tertile	All	0.565	0.665	.003	20	view →
KIRP	DFS	Tertile	IV	0.034	0.761	.026	18	view →
ESCA	DFS	Quartile	III,IV	0.217	0.433	<.001	18	view →
COAD	DFS	Median	All	0.734	0.830	.005	12	view →
ACC	OS	Median	All	0.802	0.934	.005	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

SNORA59A–KICH (OS)

Open the KICH breakdown →