Across TCGA pan-cancer cohorts, SNORA2A RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated SNORA2A data layer.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SNORA2A RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNORA2A expression acts as an unfavorable survival marker, although some lineages such as BLCA and UCS show a favorable association.
KIRC, BLCA, and UVM are the cancer types where SNORA2A RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.