SNORA22C

Across TCGA pan-cancer cohorts, SNORA22C RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated SNORA22C data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher SNORA22C RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNORA22C expression acts as an unfavorable survival marker, although some lineages such as KIRP and BRCA show a favorable association.

DLBC, MESO, and THCA are the cancer types where SNORA22C RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Tertile	All	0.110	0.959	<.001	90	view →
MESO	DFS	Median	III,IV	0.238	0.500	<.001	66	view →
THCA	DFS	Tertile	All	0.889	0.968	.001	50	view →
ACC	DFS	Tertile	III,IV	0.100	0.544	<.001	36	view →
KICH	DFS	Quartile	III,IV	0.300	0.885	.007	27	view →
READ	DFS	Tertile	IV	0.249	0.708	.008	18	view →
LUSC	DFS	Tertile	III,IV	0.230	0.476	.013	13	view →
LUAD	OS	Quartile	All	0.570	0.732	.005	13	view →
KIRP	DFS	Tertile	All	0.967	0.879	.006	12	view →
PRAD	DFS	Quartile	All	0.827	0.905	.010	12	view →
BRCA	DFS	Quartile	IV	1.000	0.620	.008	11	view →
CHOL	OS	Quartile	III,IV	0.136	0.799	.017	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

SNORA22C–DLBC (DFS)

Open the DLBC breakdown →