Across TCGA pan-cancer cohorts, SNORA19 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SNORA19’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where SNORA19 RNA is repressed in tumor relative to normal tissue. In most cancer types SNORA19 is over-expressed in tumor, although a few such as KIRP and READ show the opposite, repressed pattern.

KIRP, BLCA, and READ are the cancer types where SNORA19 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORA19 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	II,III,IV	−0.280	.005	6	view →
BLCA	All	III,IV	+0.422	.026	3	view →
READ	All	III,IV	−0.554	.022	2	view →
LUAD	All	All	+0.389	.011	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: SNORA19 RNA expression & survival · all SNORA19 data types