SNORA15B-2

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SNORA15B-2 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SNORA15B-2 data layer compared with 14 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher SNORA15B-2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SNORA15B-2 expression acts as an unfavorable survival marker.

STAD, COAD, and LIHC are the cancer types where SNORA15B-2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADOSMedianIII,IV0.0010.633<.00124view →
COADOSMedianII,III,IV0.0010.860<.00124view →
LIHCOSMedianAll0.0170.784<.00112view →
THYMDFSMedianAll0.1070.872<.0016view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration