SNORA15B-2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORA15B-2 mutation is significantly associated with the RNA expression of many other genes, with 204 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORA15B-2-associated genes across cancer lineages are MIR6507, MIR3118-3, and MTA2. Each is linked with SNORA15B-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORA15B-2-to-partner and partner-to-SNORA15B-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORA15B-2→partner) and Y-score (partner→SNORA15B-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMIR6507 →+0.359+8.055<.001.00731
BRCAMIR3118-3 →+0.558+8.471<.001.00531
UCECMTA2 →+0.557+3.212.001.00931
UCECDDAH1 →+0.810+3.191.009.00931
UCECLSS →+0.717+3.502.001.00231
UCECRUSC1 →+0.831+3.212<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 204 associations by consensus.

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