Across TCGA patient cohorts, SNORA15B-1 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORA15B-1-associated genes across cancer lineages are JNK_pT183_Y185, MEK1, and MSH2. Each is linked with SNORA15B-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORA15B-1-to-partner and partner-to-SNORA15B-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORA15B-1→partner) and Y-score (partner→SNORA15B-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.182	-2.222	.005	.010	3	1
UCEC	MEK1 →	+0.296	+2.584	.039	.010	3	1
UCEC	MSH2 →	-0.209	-2.973	.021	.035	3	1
UCEC	mTOR_pS2448 →	-0.145	-1.980	.013	.030	3	1
UCEC	NF-kB-p65_pS536 →	-0.389	-1.990	.029	.030	3	1
UCEC	PCNA →	+0.226	+2.321	.007	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

SNORA15B-1 survival (RNA) · tumor vs normal (RNA) · all SNORA15B-1 data types