Across TCGA pan-cancer cohorts, SNORA14A RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated SNORA14A data layer.
The strongest signal is observed in uveal melanoma (UVM), where higher SNORA14A RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNORA14A expression acts as an unfavorable survival marker, although some lineages such as TGCT and BLCA show a favorable association.
UVM, ACC, and KIRP are the cancer types where SNORA14A RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.