Across TCGA pan-cancer cohorts, SNORA11B RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SNORA11B’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where SNORA11B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNORA11B is over-expressed in tumor.

LUAD, BRCA, and COAD are the cancer types where SNORA11B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORA11B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	IV	+0.780	.005	4	view →
BRCA	Female	All	+0.186	.029	4	view →
COAD	All	III,IV	+0.168	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SNORA11B RNA expression & survival · all SNORA11B data types