Across TCGA pan-cancer cohorts, SNORA11 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated SNORA11 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher SNORA11 RNA is associated with better overall survival. In most high-consensus cancer types, elevated SNORA11 expression acts as an unfavorable survival marker, although some lineages such as BRCA and UCS show a favorable association.

BRCA, ESCA, and KIRC are the cancer types where SNORA11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Quartile	III,IV	0.825	0.397	<.001	54	view →
ESCA	DFS	Tertile	III,IV	0.268	0.634	<.001	48	view →
KIRC	DFS	Tertile	All	0.549	0.697	.003	40	view →
LIHC	DFS	Quartile	All	0.353	0.578	<.001	40	view →
UCS	DFS	Quartile	II,III,IV	0.598	0.150	.003	24	view →
BLCA	OS	Quartile	III,IV	0.785	0.572	.005	21	view →
UVM	DFS	Median	III,IV	0.208	0.740	.006	20	view →
PAAD	DFS	Tertile	All	0.499	0.250	.008	19	view →
PRAD	DFS	Tertile	All	0.644	0.882	.002	18	view →
READ	DFS	Median	All	0.351	0.856	<.001	11	view →
SKCM	DFS	Tertile	All	0.240	0.147	.013	11	view →
COAD	OS	Tertile	II,III,IV	0.696	0.857	.025	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

Exploration

Same gene, other analysis: SNORA11 tumor-vs-normal RNA expression · all SNORA11 data types