Across TCGA pan-cancer cohorts, SNORA10B RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SNORA10B’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where SNORA10B RNA is repressed in tumor relative to normal tissue. In most cancer types SNORA10B is over-expressed in tumor, although a few such as LUSC and STAD show the opposite, repressed pattern.

LUSC and STAD are the cancer types where SNORA10B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORA10B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	II,III,IV	−0.169	.017	2	view →
STAD	Female	III,IV	−0.760	.004	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SNORA10B RNA expression & survival · all SNORA10B data types