Across TCGA pan-cancer cohorts, SNN Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SNN data layer compared with 19 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher SNN Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SNN expression acts as an unfavorable survival marker.

STAD, UCEC, and ACC are the cancer types where SNN Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	All	0.003	0.688	<.001	36	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
ACC	DFS	Median	All	0.089	0.666	.017	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SNN tumor-vs-normal RNA expression · all SNN data types