Across TCGA patient cohorts, SNN RNA expression is significantly associated with the protein abundance of many other proteins, with 12,106 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNN-associated proteins across cancer lineages are MARCKSL1_T85, NOP56, and GNE. Each is linked with SNN in more than 4 cancer types. Because this analysis shows association rather than direction, both SNN-to-partner and partner-to-SNN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SNN→partner) and Y-score (partner→SNN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MARCKSL1_T85 →	+0.907	+0.748	<.001	<.001	3	5
BRCA	NOP56 →	-0.434	-0.682	<.001	<.001	3	4
COAD	GNE →	-0.411	-0.414	<.001	<.001	3	4
GBM	ALG2 →	-0.287	-0.741	<.001	<.001	3	4
GBM	MARCKSL1 →	+0.633	+0.628	<.001	<.001	3	4
OV	S100A6 →	-0.513	-0.398	.008	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,106 associations by consensus.

Exploration

SNN survival (RNA) · tumor vs normal (RNA) · all SNN data types