Across TCGA patient cohorts, SNN protein abundance is significantly associated with the RNA expression of many other genes, with 768 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNN-associated genes across cancer lineages are HSD17B2, CEP152, and CDC37. Each is linked with SNN in more than 1 cancer types. Because this analysis shows association rather than direction, both SNN-to-partner and partner-to-SNN results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNN→partner) and Y-score (partner→SNN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HSD17B2 →	+1.185	+0.457	.008	.008	3	2
LSCC	CEP152 →	-0.911	-0.356	<.001	.001	3	1
LSCC	CDC37 →	-0.605	-0.319	<.001	.005	3	1
LSCC	DDX49 →	-1.053	-0.319	<.001	.005	3	1
LSCC	POLR1F →	-0.786	-0.319	<.001	.005	3	1
LSCC	NUDT1 →	-0.905	-0.361	.008	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 768 associations by consensus.

Exploration

SNN survival (RNA) · tumor vs normal (RNA) · all SNN data types